Due to the rapid popularity of berberine in the dietary supplement field in recent years, many synthetic berberines have entered the market passing off as natural berberine. A recent study conducted by the University of Minnesota has found that the synthesis of berberine inevitably introduces nitrosamines, a carcinogen, which will cause irreversible damage to consumers.

Berberine hydrochloride, a natural alkaloid extracted from plants like Berberis aristata, Berberis vulgaris or Phellodendron chinense, has long been used for treating intestinal infections and diarrhea. However, its use in liver disease patients remains a contentious topic. While berberine hydrochloride offers therapeutic benefits, such as antibacterial and anti-inflammatory effects, it may also pose risks, particularly for patients with severe liver dysfunction.

Berberine hydrochloride, a natural alkaloid extracted from plants like Coptis chinensis, is well-known for its broad-spectrum antibacterial, antifungal, anti-inflammatory, and immune-regulating properties. Recent studies reveal its versatility as a functional feed additive in aquaculture, enhancing the health and productivity of aquatic animals while ensuring environmental safety.