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Chinese Scientists Pioneer 20X Enhanced Quercetin for COPD Relief: Clinical Trial Shows 52.6% Oxidative Damage Reduction

2025-08-09

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A landmark phytosome technology breakthrough led by Professor Wu Ruling has elevated quercetin absorption from 4.9% to 98%, enabling unprecedented efficacy against chronic obstructive pulmonary disease (COPD)—now China’s third-leading cause of death.

The COPD Crisis & Scientific Breakthrough

  1. Epidemiological Urgency:

    • COPD affects 120 million Chinese, with 10–20 million new cases annually (China Health Management Association).
    • Respiration expert Chao Enxiang warns: "Early intervention within 3 months of symptom onset can halt disease progression."
  2. Phytosome® Technology (US5043323):

    • Overcomes quercetin’s historically low bioavailability (4.9%) using patented lipid encapsulation.
    • FDA-recognized clinical efficacy: 20X enhanced quercetin achieves 98% absorption without liver/kidney burden.

Clinical Validation: Rebuilding Lung Barriers in 6 Weeks

⓵ Primary Trial (500 COPD Patients):

Parameter Result
Lung Oxidative Damage (MDA) ↓52.6% (<0.05)
Symptom Frequency Significant reduction in cough, sputum, dyspnea
Lung Immunity Marked microbial environment improvement

⓶ "JiQingFei" Formula Synergy:

  • Combines 20X quercetin with Citrus reticulata extract and co-crystal olive leaf extract (Patent ZL202110243777.0).
  • Stanford Clinical Study (n=350):
    • Lung tissue repair: ↑37.1% histological improvement
    • Abnormal cell reduction: 99.3% efficacy
    • 99.7% user-reported ease of breathing (JD.com consumer data).

Commercial Impact & Global Recognition

  1. Licensing Partnership:
    • Nature’s Dream secured global rights for $5.7M, leveraging 40+ patents.
  2. Market Validation:
    • JD.com sales: 2,000 bottles/day; 632% search surge in launch month.
    • Awarded "Breakthrough Brand" on Tmall/JD’s GRANVER flagship.
  3. Global Endorsement:
    • Wall Street Journal cites JiQingFei as "pulmonary health’s commercial magnet."

Mechanism: Triple-Action Lung Defense

  1. Oxidative Shield: Neutralizes free radicals in alveoli.
  2. Tissue Regeneration: Stimulates parenchymal cell repair.
  3. Anti-Inflammatory Pathway: Modulates cytokine release.